STEP 1: Prepare the Seafood

Start by cooking the seafood. Heat 2 tablespoons of olive oil in a large skillet over medium heat. Add the garlic and sauté for about 1 minute until fragrant. Add the shrimp, scallops, and fish pieces to the skillet, seasoning with oregano, salt, and pepper. Cook for about 4-5 minutes, stirring occasionally, until the shrimp turns pink, the scallops are opaque, and the fish is flaky. The seafood should be cooked through but not overdone.

Once the seafood is cooked, remove it from the heat and stir in fresh parsley for added freshness. Set the seafood aside to cool slightly while you prepare the béchamel sauce.

STEP 2: Make the Béchamel Sauce

In a separate saucepan, melt 1/4 cup of butter over medium heat. Once melted, whisk in the 1/4 cup of flour to create a smooth roux. Cook the roux for 2-3 minutes, whisking constantly to ensure it doesn’t burn.

Slowly add the 4 cups of whole milk while continuing to whisk to avoid lumps. Allow the mixture to cook, stirring frequently, until it thickens—about 5-7 minutes. Once thickened, stir in the garlic powder, onion powder, nutmeg, and salt and pepper to taste. Finally, add 1 cup of grated Parmesan cheese, stirring until melted and smooth.

If the sauce feels too thick, you can add a little more milk to reach your desired consistency. This creamy sauce will provide a rich base for the lasagna.

STEP 3: Assemble the Lasagna

Preheat your oven to 375°F (190°C). Lightly grease a 9×13-inch baking dish with cooking spray or olive oil.

Start by spreading a small amount of the béchamel sauce in the bottom of the baking dish. Then, layer 4 lasagna noodles over the sauce, followed by a third of the seafood mixture. Spoon some of the béchamel sauce over the seafood, followed by a sprinkle of mozzarella cheese and a spoonful of ricotta cheese if you’re using it.

Repeat this layering process two more times: a layer of noodles, seafood, béchamel sauce, and cheeses. Finish with a final layer of noodles and top with the remaining béchamel sauce, mozzarella cheese, and Parmesan cheese.

STEP 4: Bake the Lasagna

Cover the baking dish with aluminum foil, making sure it doesn’t touch the cheese. Bake in the preheated oven for 25-30 minutes.

After the initial baking time, remove the foil and bake for an additional 15-20 minutes until the top is golden and bubbly. The lasagna should be hot throughout and the cheese melted.

STEP 5: Rest and Serve

Once the lasagna is done, let it rest for about 10 minutes before slicing. This resting time allows the layers to set and makes serving easier.

Serve the lasagna with a light green salad on the side and perhaps a glass of white wine like Chardonnay or Pinot Grigio for a refreshing complement to the creamy and rich flavors of the dish.